The global Tangential Flow Filtration market size was valued at USD 1,900 million in 2022 and is projected to reach USD 3,800 million by 2033, growing at a CAGR of 14.1% during the forecast period.
Tangential flow filtration (TFF), also known as cross-flow filtration, is a filtration technique used to separate and purify biomolecules, nanoparticles, and other particulate matter from liquid solutions. TFF involves the use of a porous membrane through which the feed solution is passed, while a transmembrane pressure is applied to promote the flow of solvent and small molecules through the membrane, leaving behind the larger particles. The biopharmaceutical industry is experiencing significant growth, driven by factors such as the aging population, rising prevalence of chronic diseases, and advancements in biotechnology. TFF is widely used in the biopharmaceutical manufacturing process for downstream purification, leading to increased demand for TFF systems. Continuous innovation and technological advancements in TFF systems, including membrane materials, module design, and automation capabilities, have improved process efficiency, scalability, and product yield. These advancements have positively influenced the growth of the TFF market.
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The market is witnessing a trend towards the adoption of single-use TFF systems. Single-use systems offer benefits such as reduced cleaning and validation requirements, faster turnaround times, and increased flexibility in manufacturing processes. They are particularly favored in biopharmaceutical production, where minimizing cross-contamination and improving operational efficiency are essential.
There is a growing trend of integrating automation and control systems into TFF processes. Automated TFF systems streamline process control, data monitoring, and data logging, enabling real-time process adjustments and enhancing reproducibility. Automation also reduces the risk of human error and improves overall process efficiency.
Segmental Analysis
Product Type
• TFF systems
• membrane filters
• filtration accessories
• others
Membrane Type
• Polyethersulfone (PES)
• regenerated cellulose
• ceramic
• others
Operation Mode
• Batch TFF
• continuous TFF.
End-user
• Biopharmaceutical companies
• contract research organizations (CROs)
• academic and research institutes
• others.
Key Companies
• Merck KGaA
• Danaher Corporation (Pall Corporation)
• Sartorius AG
• Repligen Corporation
• GE Healthcare
• Thermo Fisher Scientific Inc.
• 3M Company
• Alfa Laval AB
• Parker Hannifin Corporation
• Cole-Parmer Instrument Company LLC
• Others.
Regional Scope
North America
• U.S.
• Canada
• Mexico
Europe
• U.K.
• Germany
• France
• Italy
• Spain
• Rest of Europe
Asia Pacific
• China
• India
• Japan
• South Korea
• Australia
• Rest of Asia Pacific
South America
• Brazil
• Argentina
• Rest of South America
Middle East and Africa
• Saudi Arabia
• UAE
• Egypt
• South Africa
• Rest of Middle East and Africa
Recent Developments
• In 2022, High Purity New England (HPNE) has introduced a modular and adaptable tangential flow filtration (TFF) system called OptiMaxx. This off-the-shelf system aims to revolutionize downstream bioprocessing by offering open architecture and customization options. According to Emily Peterson, the BD manager of the OptiMaxx product line, the system’s versatility allows it to be easily configured to meet various processing needs, whether it involves single-use or multi-use applications or utilizing different sensors and filters available in the market. OptiMaxx stands out due to its adaptability, and it is available in a wide range of sizes, spanning from 1mL to 120L/min.
Why to buy this Report?
The report provides quantitative and qualitative aspect for the market in terms of value and volume, along with supporting market trends, challenges, restraints.
The report provides an in depth analysis from both production and consumption point of view at the regional and country level. Key Factors considered within the report scope are Production capacity by countries/regions, average price, consumption ratio, revenue earned and gross margin.
The report provides competitive analysis of around 30-50 companies operated in the market, these companies are bifurcated into niche players, the leaders and major contenders.
The companies are analyzed in terms of following factors such as:
• Business Model
• Production Capacity, Revenue, Sales, Gross Margin
• Key Business Strategy
• SWOT Analysis
In terms of competitive landscape, the report provides distinctive factors that would help the end user in taking a key decision within the business:
• Company Share Analysis from 2018-2022
• Company Analysis by Revenue and Sales
• Company Production Capacity, Gross Margin
• Company Share Analysis by Application/End Use
• Company Share Analysis by Product/Specification.
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